Go to your genymotion emulator

Settings -> Wifi -> Press and hold your active network

Select “Modify Network”

Select “Show Advanced Options”

Select “Proxy Settings -> Manual”

Set your Proxy to: 10.0.3.2 (Genymotion’s special code for the local workstation. the Network mode must be NAT on virtual device configuration)

Set your Port to: 8888

Press Save.

Although after this you will see the network requests logged in charlesproxy . Open the genymotion browser and go the following URL http://charlesproxy.com/getssl to download and install the certificate . you should be good to go . Copied from :http://rexstjohn.com/using-genymotion-charles-proxy/

Updated 21.07.2016 reflecting changes since Charles 3.10

For enabling plain text communication on SSL connections Charles act as a Man in the Middle. After you have managed your device to communicate via Charles http proxy, you need to download and install certificate from your running instance of Charles, its generated and signed by a Charles Root Certificate.

Basically there are two ways possible (I prefer the first one):

Download and install directly on device

Device has to be configured to communicate via Charles!

1. start browser
2. open http://charlesproxy.com/getssl
3. certificate download will be started
4. confirm insertion dialog

Save the certificate from Charles UI

1. save the certificate via "Help -> SSL Proxying -> Save Charles Root Certificate.."
2. put it on a device (via adb push, email ....) and click on the file in order to install it.

Note 1: After install the certificate you will be forced to create a security Pin/Pattern/Password for the device.

Note 2: Since Charles v3.10 single SSL Root Certificates aren't supported anymore.

It's tricky to setup properly on genymotion device, but here is the steps:1. Start Genymotion device2. Go to Setting -> Wifi -> Hold or open Advance Tab3. Proxy Setting and select Manual4. Config to the port of Mitm app. Charles is 8888, Proxyman is 90905. Install the certificate at:- http://charlesproxy.com/getssl for Charles- http://proxy.man/ssl for Proxyman6. Accept the Certificate 7. Test again.

Basically, those steps are consistent from Charles Proxy and Proxyman. Hopefully it could help you.