Upload Timeout Issue Under Apache/Perl
"Connection reset by peer" often indicates the user stopped waiting for the upload to complete by hitting stop or navigating away.
You can try to increase "Timeout" setting in Apache's config in case it's just the network having slowness spikes.
Also, please see this: http://www.mail-archive.com/apreq-dev@httpd.apache.org/msg00457.html - there might be a 64MB limit according to that post though I don't see any corroborating evidence.
Also, see this example on how to set read limit: http://permalink.gmane.org/gmane.comp.apache.mod-perl/24260