I just wanted to add to the answers already given, having just gone through this process with an ASP.NET MVC 5 project.

Uninstall Using NuGet

As the other answers say, the best way to remove Application Insights is through Nuget: Tools -> NuGet Package Manager -> Manage NuGet Packages for Solution.

I found it best to remove Microsoft.ApplicationInsights.Web and all its dependencies first, then Microsoft.ApplicationInsights.Javascript API.

This removed everything except:

• the ApplicationInsights.config file,
• a script snippet in _Layout.cshtml,

both of which I removed manually.

What Microsoft has to say

The Microsoft Azure documentation here: https://azure.microsoft.com/en-gb/documentation/articles/app-insights-troubleshoot-faq/, says:

What does Application Insights modify in my project?

The details depend on the type of project. For a web application:

Adds these files to your project:

• ApplicationInsights.config.
• ai.js

Installs these NuGet packages:

• Application Insights API - the core API
• Application Insights API for Web Applications - used to send telemetry from the server
• Application Insights API for JavaScript Applications - used to send telemetry from the client

The packages include these assemblies:

• Microsoft.ApplicationInsights
• Microsoft.ApplicationInsights.Platform

Inserts items into:

• Web.config
• packages.config (New projects only - if you add Application Insights to an existing project, you have to do this manually.) Inserts snippets into the client and server code to initialize them with the Application Insights resource ID. For example, in an MVC app, code is inserted into the master page Views/Shared/_Layout.cshtml

Remove Manually

To remove Application Insights without NuGet, or if like me you don't trust it and want to know which files are removed, I followed these steps:

• Remove application insights from the web.config, under system.webserver.modules, search for ApplicationInsightsWebTracking.

• Remove all Microsoft.AI (Application Insights) prefixed references from project references.

• Remove all Microsoft.ApplicationInsights packages from package.config.

• Delete ApplicationInsights.config file.

• Remove script from _Layout.cshtml:

  var appInsights=window.appInsights||function(config){    function r(config){t[config]=function(){var i=arguments;t.queue.push(function(){t[config].apply(t,i)})}}var t={config:config},u=document,e=window,o="script",s=u.createElement(o),i,f;for(s.src=config.url||"//az416426.vo.msecnd.net/scripts/a/ai.0.js",u.getElementsByTagName(o)[0].parentNode.appendChild(s),t.cookie=u.cookie,t.queue=[],i=["Event","Exception","Metric","PageView","Trace"];i.length;)r("track"+i.pop());return r("setAuthenticatedUserContext"),r("clearAuthenticatedUserContext"),config.disableExceptionTracking||(i="onerror",r("_"+i),f=e[i],e[i]=function(config,r,u,e,o){var s=f&&f(config,r,u,e,o);return s!==!0&&t["_"+i](config,r,u,e,o),s}),t}({    instrumentationKey:"RemovedKey"});window.appInsights=appInsights;appInsights.trackPageView();

• Remove ai.0.15.0-build58334.js & ai.0.15.0-build58334.min.js from Scripts directory.

• Clean & Rebuild all.

Unless I'm misunderstanding the question, you should only have to remove one extension and possibly one nuget package.

Uninstall the Application Insights Tools for Visual Studio extension and remove the Application Telemetry SDK for Services nuget package. The telemetry package is installed along with Application Insights but must be removed separately.

In my experience the telemetry package is not required if you wish to keep using Application Insights' other features. Removing the telemetry package will stop all telemetry logging but Application Insights will continue to report non-telemetry information just fine.

I would prefer to do this:

UnInstall-Package Microsoft.ApplicationInsights.Web -RemoveDependencies