When should you use Page.DataBind() versus Control.DataBind()?

Page.DataBind is Control.DataBind. Neither the Page class, nor the TemplateControl class overrides Control.DataBind.

Control.DataBind does little more than call OnDataBinding for the control, then it calls DataBind for each child control.

For choosing between Page.DataBind() versus Control.DataBind(), here is the Microsoft guidance :

"Both methods work similarly. The main difference is that all data sources are bound to their server controls after the Page.DataBind method is called. No data is rendered to the control until you explicitly call either the DataBind method of the Web server control or until you invoke the page-level Page.DataBind method. Typically, Page.DataBind (or DataBind) is called from the Page_Load event."

There will be cases when you want specify control databinding individually, depending on the current page scenario. For a detailed level of control over which controls are bound and when controls are bound, I opt for the control-level DataBind() methods.

In an ASP.NET page, you can bind directly to public/protected properties of your page's code-behind class. For example:

<form id="form1" runat="server"><%#HtmlUtility.HtmlEncode(MyProperty.ToString())%></form>

In this case, there is no specific control to call .DataBind() on - the page itself is the control. It just so happens that calling Page.DataBind() will also call DataBind() on all child controls, so if you're already doing a Page.DataBind(), there's no need to data bind the controls individually.