You'll want to add a Reply-To header to the EmailMessage.
Reply-To
EmailMessage
headers = {'Reply-To': reply_email}msg = EmailMessage(subject, body, from_email, [to_email], headers=headers)msg.content_subtype = "html"msg.send()
As of Django 1.8 there is an argument that can be passed into the constructor of EmailMessage named reply_to that will handle the headers logic for you.
reply_to