I am facing issues while hosting my Flask web application in IIS
Add applicationHost.xdt under Your Project directory..
applicationHost.xdt
<?xml version="1.0"?><configuration xmlns:xdt="http://schemas.microsoft.com/XML-Document-Transform"> <system.webServer> <fastCgi> <application xdt:Locator="Match(fullPath)" xdt:Transform="SetAttributes(activityTimeout)" fullPath="C:\Program Files\Python35\python.exe" activityTimeout="600"/> </fastCgi> </system.webServer></configuration>Refresh and Restart your Site.Now it will work..