What is "request.args" and how is it used?

According to the flask.Request.args documents.

flask.Request.args
A MultiDict with the parsed contents of the query string. (The part in the URL after the question mark).

So the args.get() is method get() for MultiDict, whose prototype is as follows:

get(key, default=None, type=None)

Update:
In newer version of flask (v1.0.x and v1.1.x), flask.Request.args is an ImmutableMultiDict(an immutable MultiDict), so the prototype and specific method above are still valid.

@martinho as a newbie using Flask and Python myself, I think the previous answers here took for granted that you had a good understanding of the fundamentals. In case you or other viewers don't know the fundamentals, I'll give more context to understand the answer...

... the request.args is bringing a "dictionary" object for you. The "dictionary" object is similar to other collection-type of objects in Python, in that it can store many elements in one single object. Therefore the answer to your question

And how many parameters request.args.get() takes.

It will take only one object, a "dictionary" type of object (as stated in the previous answers). This "dictionary" object, however, can have as many elements as needed... (dictionaries have paired elements called Key, Value).

Other collection-type of objects besides "dictionaries", would be "tuple", and "list"... you can run a google search on those and "data structures" in order to learn other Python fundamentals. This answer is based Python; I don't have an idea if the same applies to other programming languages.

request.args is a MultiDict with the parsed contents of the query string. From the documentation of get method:

get(key, default=None, type=None)

Return the default value if the requested data doesn’t exist. If type is provided and is a callable it should convert the value, return it or raise a ValueError if that is not possible.