Google searches with permanent filters
You can create a Custom Search in minutes. It's called Google CSE (Custom Search Engine)
This is a sample public link that I've created based on your example above: https://www.google.com/cse/publicurl?cx=006201654654568968489:1kv4asuwfvs
In the settings:
I can choose to exclude by url, url pattern, or even urls within my search results
If you need more ways, here's a good and relevant link.
Search filters can be specified as part of the URL (e.g. append site:example.com/section1 to a Google query to only yield results whose locations start with that prefix). So you can make a search plugin that substitutes your query into such a template and install it into your browser.
Search plugins are generally XML files with a standardized schema. OpenSearch is one such standard supported by Chrome.
There are sites that host collections of user-submitted plugins as well as tools to generate your own. An example that I use is the Mycroft project (originally created for Apple Sherlock software that pioneered the concept and later accepted into the Mozilla project when Firefox took on the feature).