How can I tell Flash Builder to debug a SWF in a new browser window?
On MacOS X, Chrome only starts once. So, with your startup options, you get this error:
Unable to obtain profile lock.
The origin of this error is explained here.
A solution is to use a different data dir for your debugging sessions:
--user-data-dir=<PATH TO DATA DIR>
For example in your home directory (something like /Users/username/chrome-debug-datadir). That solved the problem here.You need to configure Chrome once in the new data dir. It also gives a clean separation between developing / debugging sessions and regular Chrome sessions.