Should small companies code their sites to support Chrome?
Write code to standards first, then for different rendering engines if needed. Never design websites for specific browsers, it's a very slippery slope.
its a good reason to improve support for WebKit browsers in general (do you not have any customers using Safari on a Mac?)
Chrome is still in early beta and it's rendering is not bug free, I also experience critical UI issues in Chrome. I do plan on my web apps working in Chrome, but I've made a decision not to change anything until Chrome hits a more mature level.
Google has recently said they will be bringing Chrome to a non beta state very soon (unlike their past history of leaving things in beta for 5yrs or so).
Also, if you plan on using Chrome to webdev in this beta state, you'll want to install the "Developer Channel" which gives you access to a newer versions than the public version, very important at this stage of the browser. As of 12/10/2008 the dev version of Chrome is 0.4.154.33