dyld: Library not loaded: /usr/local/opt/openssl/lib/libssl.1.0.0.dylib when running nginx and mysql after macOS upgrade to Catalina
I had the same issue, not for upgrading to Catalina but because of installing a program which upgrade my version of OpenSSL, so it brokes other apps which depended on OpenSSL. In my case Ruby (2.3.8 with RVM) and MySQL (MariaDb in fact). In the case of Ruby, it was incompatible with the new version of OpenSSL, so I had to install it with pkg depdendencies for RVM
rvm pkg install opensslrvm reinstall 2.3.8 --with-openssl-dir=$HOME/.rvm/usrIn the case of MySQL I just upgraded it, so it got installed with the new openSSL on my System.
brew upgrade mariadbThats solves my issues. I think in your case you could upgrade (or uninstall and reintall) MySQL and Nginx, so they will correctly use the new version of OpenSSL.
(P.D. In the case of MySQL it conserved my databases without problems)