Automation Solution for both Web and WPF Applications
It is definitely possible to use Selenium (C#) with MS UI Automation. There would not be much in common besides code that you write yourself, but personally I think that this approach is a good idea if you are a strong programmer. MS UI Automation is not easy at all. An alternative would be to consider Silk4Net. You could use it for web and WCF, but if you wanted to use Selenium for web and Silk4Net for WCF, that would work. Just the plain ole Silk4Net 'library usuage' license is reasonably priced.