Connect django website/database with desktop application
Have you considered Electron for the desktop app? Electron is basically a framework for using web technologies to build desktop applications and is used for things like Slack and Visual Studio Code.
It seems perfect for this purpose. You could just create a custom app in Django for the management of the database that can only be accessed via the Electron client. The entire desktop application could be built as a webpage and justed linked to in Electron.