How do I get the UI thread's Dispatcher?

You can grab the UI Dispatcher from the static application instance: Application.Current.Dispatcher

You may want to check Application.Current for null first, as it can be cleared during a shutdown sequence.

The following works much better for me when being used in a WinForms application that happens to be also using WPF (in my case Esri's Arcmap.exe)

private System.Windows.Threading.Dispatcher Dispatcher { get; set; }// I put this in my view model constructor as it MUST be called from UI threadDispatcher = System.Windows.Threading.Dispatcher.CurrentDispatcher;

The other method (which involved calling new System.Windows.Application() to populate System.Windows.Application.Current) caused issues for me every time I opened a new WPF window and then closed it. Not only did this null out System.Windows.Application.Current, but I could no longer open up new windows as their InitializeComponents() methods, all failed with:

System.InvalidOperationException: 'The Application object is being shut down.'

So far the new solution is working without those side effects.